Enzyme transformer

Enzymes speed up or catalyze biochemical reactions.  Most enzyme are highly complicated protein molecules and many enzymes approximate catalytic perfection.  You can learn more about enzymes - specifically, the enzyme carbonic anhydrase - by watching this video:

 

Now, the conventional wisdom on enzymes is that a single enzyme adopts a single structure that subserves a single function.  As if the conventional wisdom were not fascinating enough, new research indicates that an enzyme from the aminoacyl-transfer RNA synthetase (tRNA synthetases) family can adopt two distinct structures to perform two very different functions.  In essence, researchers have discovered a transformer enzyme with the ability to shape shift and perform different functions in the cell.  Clearly, these findings will have theoretical and experimental implications for biochemistry and biophysics.  Perhaps less obvious are the implications for drug discovery and clinical medicine.  You can read more about this exciting work and its potential implications by reading this popular level article.

For the scientific and technical details associated with transformer-tRNA, be sure to consult the publication referenced in the popular article linked to above:

http://www.ncbi.nlm.nih.gov/pubmed/23159739

Who ever said biochemistry was boring?

 

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